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Breast Examination Techniques (2023)

D.DizdarogluM.LunecJ

Nevertheless, the regulation (direct or indirect) of GPx1 by Nrf2-linked pathways is intriguing as GPx1 can modulate oxidant stress to mitigate Nrf2 activation

For instance, modulating glucose uptake and utilization in neurons via the AMPK signaling pathway, or enhancing mitochondrial metabolic flux through PGC-1-dependent mitochondrial biogenesis, could offer neuroprotective effects under metabolic stress or neurodegenerative conditions (Lee and Silva, 2009)